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ROBOS '25, The 7th Raab Outer Banks Oncology Symposium: Early Afternoon Sessions, July 11

July 11-12, 2025

Conference Brochure

                                                                                                                          

Systemic Treatment for Metastatic Colorectal Cancer (CRC) Paradigm Shifts

Items 1-15 of 15 (Display the 15 citations in PubMed)

1.

Improving our understanding of the quality of life of patients with metastatic or recurrent/persistent anal cancer: a systematic review.

Sodergren SC, Edwards R, Krishnatry R, Guren MG, Dennis K, Franco P, de Felice F, Darlington AS, Vassiliou V.

Support Care Cancer. 2025 May 15;33(6):475. doi: 10.1007/s00520-025-09520-8.

PMID: 40372578 Free PMC article. Review.

2.

Second-line systemic treatment for metastatic colorectal cancer: A systematic review and Bayesian network meta-analysis based on RCT.

Sun C, Fan E, Huang L, Zhang Z.

PLoS One. 2024 Dec 23;19(12):e0313278. doi: 10.1371/journal.pone.0313278. eCollection 2024.

PMID: 39715232 Free PMC article.

3.

Multidisciplinary Delphi Consensus on Safety of Combining Transarterial Radioembolization with Yttrium-90 Microspheres with Systemic Anticancer Agents for the Treatment of Liver Malignancy.

Kennedy AS, Brown DB, Fakih M, Jeyarajah R, Jones S, Liu D, Pinato DJ, Sangro B, Sharma NK, Sze DY, Van Cutsem E, Wasan HS.

J Vasc Interv Radiol. 2024 Sep;35(9):1253-1267.e1. doi: 10.1016/j.jvir.2024.06.006. Epub 2024 Jun 15.

PMID: 38885899

4.

A critical appraisal of the current landscape of resectable BRAF mutated colorectal liver metastases: a systematic review.

Margonis GA, Wang J, Papakonstantinou D, Beyer K, Kreis ME, D'Angelica M.

Chin Clin Oncol. 2024 Aug;13(4):51. doi: 10.21037/cco-23-128. Epub 2024 May 28.

PMID: 38859602 Free PMC article.

5.

Cytoreductive surgery plus hyperthermic intraoperative peritoneal chemotherapy for people with peritoneal metastases from colorectal, ovarian or gastric origin: A systematic review of randomized controlled trials.

Gurusamy K, Leung J, Vale C, Roberts D, Linden A, Tan XW, Taribagil P, Patel S, Pizzo E, Davidson B, Saunders M, Aziz O, O'Dwyer ST.

World J Surg. 2024 Jun;48(6):1385-1403. doi: 10.1002/wjs.12186. Epub 2024 Apr 24.

PMID: 38658171 Free PMC article.

6.

Outcomes of Hepatic Artery-Based Therapies and Systemic Multiagent Chemotherapy in Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis.

Sugumar K, Stitzel H, Wu V, Bajor D, Chakrabarti S, Conces M, Henke L, Lumish M, Mahipal A, Mohamed A, Winter JM, Hardacre JM, Ammori JB, Selfridge JE, Ocuin LM.

Ann Surg Oncol. 2024 Jul;31(7):4413-4426. doi: 10.1245/s10434-024-15187-y. Epub 2024 Mar 19.

PMID: 38502296 Free PMC article.

7.

Microwave coagulation for liver metastases.

Storman D, Swierz MJ, Mitus JW, Pedziwiatr M, Liang N, Wolff R, Bala MM.

Cochrane Database Syst Rev. 2024 Mar 27;3(3):CD010163. doi: 10.1002/14651858.CD010163.pub3.

PMID: 38534000 Free PMC article. Review.

8.

Impacts of systemic treatments on health-related quality of life for patients with metastatic colorectal cancer: a systematic review and network meta-analysis.

Jiang Y, Zhao M, Tang W, Zheng X.

BMC Cancer. 2024 Feb 9;24(1):188. doi: 10.1186/s12885-024-11937-z.

PMID: 38336718 Free PMC article.

9.

A Systematic Review and Meta-Analysis of Trifluridine/Tipiracil plus Bevacizumab for the Treatment of Metastatic Colorectal Cancer: Evidence from Real-World Series.

Voutsadakis IA.

Curr Oncol. 2023 May 24;30(6):5227-5239. doi: 10.3390/curroncol30060397.

PMID: 37366880 Free PMC article. Review.

10.

Cancer-directed surgery in patients with metastatic cancer: A systematic review and meta-analysis of randomized evidence.

Abel MK, Myers EL, Minkin E, Tahir P, Haynes AB, Wright JD, Rauh-Hain JA, Melamed A.

Cancer Med. 2023 Jul;12(13):14072-14083. doi: 10.1002/cam4.6061. Epub 2023 Jun 13.

PMID: 37309837 Free PMC article.

11.

Treatment of Metastatic Colorectal Cancer: ASCO Guideline.

Morris VK, Kennedy EB, Baxter NN, Benson AB 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C.

J Clin Oncol. 2023 Jan 20;41(3):678-700. doi: 10.1200/JCO.22.01690. Epub 2022 Oct 17.

PMID: 36252154 Free PMC article.

12.

Overall Survival in Phase 3 Clinical Trials and the Surveillance, Epidemiology, and End Results Database in Patients With Metastatic Colorectal Cancer, 1986-2016: A Systematic Review.

Shen C, Tannenbaum D, Horn R, Rogers J, Eng C, Zhou S, Johnson B, Kopetz S, Morris V, Overman M, Parseghian C, Chang GJ, Lopez-Olivo MA, Kanwal R, Ellis LM, Dasari A.

JAMA Netw Open. 2022 May 2;5(5):e2213588. doi: 10.1001/jamanetworkopen.2022.13588.

PMID: 35608860 Free PMC article.

13.

Clinical Value of Consensus Molecular Subtypes in Colorectal Cancer: A Systematic Review and Meta-Analysis.

Ten Hoorn S, de Back TR, Sommeijer DW, Vermeulen L.

J Natl Cancer Inst. 2022 Apr 11;114(4):503-516. doi: 10.1093/jnci/djab106.

PMID: 34077519 Free PMC article.

14.

Clinical outcomes of biliary drainage of malignant biliary obstruction due to colorectal cancer metastases: A systematic review.

Kastelijn JB, van der Loos MA, Welsing PM, Dhondt E, Koopman M, Moons LM, Vleggaar FP.

Eur J Intern Med. 2021 Jun;88:81-88. doi: 10.1016/j.ejim.2021.03.032. Epub 2021 Apr 27.

PMID: 33931267

15.

Conversion strategies with chemotherapy plus targeted agents for colorectal cancer liver-only metastases: A systematic review.

Bolhuis K, Kos M, van Oijen MGH, Swijnenburg RJ, Punt CJA.

Eur J Cancer. 2020 Dec;141:225-238. doi: 10.1016/j.ejca.2020.09.037. Epub 2020 Nov 12.

PMID: 33189037

Resectional Approaches to Non-CRC Liver Mets

Items 1-20 of 20 (Display the 20 citations in PubMed)

1.

Surgical results of liver metastases of tumors other than colorectal-neuroendocrine: Is it really worth it or is it necessary?

Aksoy F, Gökçe E, Balkan EA, Dündar HZ, Kaya E.

Turk J Surg. 2024 Dec 27;40(4):267-274. doi: 10.47717/turkjsurg.2024.6474. eCollection 2024 Dec.

PMID: 39980646 Free PMC article.

2.

Is There a Role for Locoregional Therapies for Non-colorectal Gastrointestinal Malignancies?

Fonseca GM, Braghiroli MIFM, Pirola Kruger JA, Coelho FF, Herman P.

Hematol Oncol Clin North Am. 2025 Feb;39(1):125-141. doi: 10.1016/j.hoc.2024.08.004.

PMID: 39510669 Review.

3.

Comparison of post-hepatectomy long-term survival outcome between non-colorectal non-neuroendocrine and colorectal liver metastases: A population-based propensity-score matching analysis.

Ng KKC, Lok HT, Lee KF, Cheung TT, Chia NH, Ng WK, Law CK, Cheung CY, Cheng KC, Cheung SYS, Lai PBS.

Surgeon. 2024 Apr;22(2):e100-e108. doi: 10.1016/j.surge.2023.11.007. Epub 2023 Dec 11.

PMID: 38081758

4.

Current status of liver surgery for non-colorectal non-neuroendocrine liver metastases: the NON.LI.MET. Italian Society for Endoscopic Surgery and New Technologies (SICE) and Association of Italian Surgeons in Europe (ACIE) collaborative international survey.

Libia A, Podda M, Di Martino M, Pata F, Pellino G, Di Saverio S, Anselmo A, Muttillo EM, De Pastena M, Campanile FC, Ielpo B, Spampinato MG; NON.LI.MET.Collaborative Study Group.

Updates Surg. 2024 Jan;76(1):43-55. doi: 10.1007/s13304-023-01649-7. Epub 2023 Oct 24.

PMID: 37875725

5.

Non-colorectal liver metastases: A review of interventional and surgical treatment modalities.

Kniepeiss D, Talakić E, Portugaller RH, Fuchsjäger M, Schemmer P.

Front Surg. 2022 Nov 2;9:945755. doi: 10.3389/fsurg.2022.945755. eCollection 2022.

PMID: 36406370 Free PMC article. Review.

6.

Non-colorectal non-neuroendocrine liver metastasis: a narrative review of surgical treatment.

Del Basso C, Usai S, Levi Sandri GB.

Chin Clin Oncol. 2022 Aug;11(4):28. doi: 10.21037/cco-22-13.

PMID: 36098099 Review.

7.

Is hepatic resection justified for non-colorectal non-neuroendocrine liver metastases? A systematic review and meta-analysis.

Ng KKC, Cheng NMY, Lok HT, Kung JWC, Fung AKY, Chan SL.

Surgeon. 2023 Jun;21(3):160-172. doi: 10.1016/j.surge.2022.05.003. Epub 2022 Jun 17.

PMID: 35718702 Review.

8.

Influence of the tumor site and histopathology after resection for non-colorectal non-neuroendocrine liver metastases. A single center experience.

De-Armas-Conde N, Ramon-Rodriguez J, Prada-Villaverde A, Jaén-Torrejimeno I, López-Guerra D, Blanco-Fernández G.

Cir Esp (Engl Ed). 2023 Jun;101(6):397-407. doi: 10.1016/j.cireng.2022.04.016. Epub 2022 Apr 29.

PMID: 35500759

9.

Surgery for Liver Metastasis of Non-Colorectal and Non-Neuroendocrine Tumors.

Katou S, Schmid F, Silveira C, Schäfer L, Naim T, Becker F, Radunz S, Juratli MA, Seifert LL, Heinzow H, Struecker B, Pascher A, Morgul MH.

J Clin Med. 2022 Mar 29;11(7):1906. doi: 10.3390/jcm11071906.

PMID: 35407514 Free PMC article.

10.

Histopathological growth patterns of resected non-colorectal, non-neuroendocrine liver metastases: a retrospective multicenter study.

Meyer Y, Bohlok A, Höppener D, Galjart B, Doukas M, Grünhagen DJ, Labar A, Lucidi V, Vermeulen PB, Verhoef C, Donckier V.

Clin Exp Metastasis. 2022 Jun;39(3):433-442. doi: 10.1007/s10585-022-10153-y. Epub 2022 Feb 6.

PMID: 35124739

11.

Surgical treatment of liver metastases from non-colorectal non-neuroendocrine carcinomas.

Bauschke A, Altendorf-Hofmann A, Homman M, Manger T, Pertschy J, Helfritzsch H, Göbel H, Settmacher U.

J Cancer Res Clin Oncol. 2022 Feb;148(2):503-515. doi: 10.1007/s00432-021-03631-5. Epub 2021 Apr 20.

PMID: 33880657 Free PMC article.

12.

The lack of selection criteria for surgery in patients with non-colorectal non-neuroendocrine liver metastases.

Bohlok A, Lucidi V, Bouazza F, Daher A, Germanova D, Van Laethem JL, Hendlisz A, Donckier V.

World J Surg Oncol. 2020 May 25;18(1):106. doi: 10.1186/s12957-020-01883-y.

PMID: 32450872 Free PMC article.

13.

Laparoscopic liver resection for non-colorectal non-neuroendocrine metastases: perioperative and oncologic outcomes.

Aghayan DL, Kalinowski P, Kazaryan AM, Fretland ÅA, Sahakyan MA, Røsok BI, Pelanis E, Bjørnbeth BA, Edwin B.

World J Surg Oncol. 2019 Sep 4;17(1):156. doi: 10.1186/s12957-019-1700-y.

PMID: 31484583 Free PMC article.

14.

Outcomes of 1,639 hepatectomies for non-colorectal non-neuroendocrine liver metastases: a multicenter analysis.

Sano K, Yamamoto M, Mimura T, Endo I, Nakamori S, Konishi M, Miyazaki M, Wakai T, Nagino M, Kubota K, Unno M, Sata N, Yamamoto J, Yamaue H, Takada T; Japanese Society of Hepato-Biliary-Pancreatic Surgery.

J Hepatobiliary Pancreat Sci. 2018 Nov;25(11):465-475. doi: 10.1002/jhbp.587. Epub 2018 Nov 20.

PMID: 30311741

15.

Outcome after hepatic resection for isolated non-colorectal, non-neuroendocrine liver metastases in 100 patients - the role of the embryologic origin of the primary tumor.

Holzner PA, Makowiec F, Klock A, Glatz T, Fichtner-Feigl S, Lang SA, Neeff HP.

BMC Surg. 2018 Oct 29;18(1):89. doi: 10.1186/s12893-018-0424-1.

PMID: 30373582 Free PMC article.

16.

Role of surgical resection for non-colorectal non-neuroendocrine liver metastases.

Takemura N, Saiura A.

World J Hepatol. 2017 Feb 18;9(5):242-251. doi: 10.4254/wjh.v9.i5.242.

PMID: 28261381 Free PMC article. Review.

17.

Liver resection for non-colorectal non-neuroendocrine metastases.

Clarke NAR, Kanhere HA, Trochsler MI, Maddern GJ.

ANZ J Surg. 2018 Apr;88(4):E313-E317. doi: 10.1111/ans.13700. Epub 2016 Aug 3.

PMID: 27490345

18.

Liver Resection for Non-colorectal Non-neuroendocrine Metastases: Where Do We Stand Today Compared to Colorectal Cancer?

Schiergens TS, Lüning J, Renz BW, Thomas M, Pratschke S, Feng H, Lee SM, Engel J, Rentsch M, Guba M, Werner J, Thasler WE.

J Gastrointest Surg. 2016 Jun;20(6):1163-72. doi: 10.1007/s11605-016-3115-1. Epub 2016 Feb 26.

PMID: 26921025

19.

Hepatectomy for liver metastases in non-colorectal, non-neuroendocrine cancer patients. The survival benefit in primary unresectable cases.

Maeda Y, Shinohara T, Katayama T, Futakawa N, Hamada T.

Int J Surg. 2015 Oct;22:136-42. doi: 10.1016/j.ijsu.2015.07.716. Epub 2015 Aug 12.

PMID: 26277530

20.

Is Hepatic Resection for Non-colorectal, Non-neuroendocrine Liver Metastases Justified?

Hoffmann K, Bulut S, Tekbas A, Hinz U, Büchler MW, Schemmer P.

Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1083-92. doi: 10.1245/s10434-015-4775-x. Epub 2015 Aug 5.

PMID: 26242369

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